In current strategies for preventing pesticide-related risks in agricultural settings, attention is too often focused on the expected benefits of technical measures—particularly personal protective equipment (PPE)—at the expense of a situated and embodied understanding of how these measures are used, how exposure occurs, their effects on farmers’ health, and the preoccupations they raise. This approach amounts to trying to solve a problem before fully understanding it. Based on intervention research in developmental ergotoxicology and anthropology, this article analyzes the real and sensitive work of farmers in situations involving the use of PPE. Far from being neutral objects, PPE condense tensions between regulatory prescriptions, toxic exposures, and widespread collective beliefs in standardized protection. They reveal the formal and informal, material and symbolic dimensions of toxic risk regulation practices. To design truly effective and sustainable prevention systems, it is essential to take these dimensions into account and to integrate sensitive knowledge, embodied experiences, and the field-based concerns of agricultural workers. The sensitive reading proposed here combines a developmental ergotoxicological approach, anthropotechnology, sensory anthropology, and a choreographic perspective. It opens new avenues for analysis and intervention by recognizing the active role of male and female farmers in reshaping prevention practices, design processes, and public policy.